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GENETICALLY MODIFIED ORGANISMS (GMOs)
Published on October 11, 2001

What are GMOs?

At present, genetically modified organisms (GMOs) are a serious issue of debate in countries around the world. The debate over GMOs has been separated into two distinct sides. Anti-GMO supporters fight to rid the world's food system of GMOs in order to protect society against the possible long-term damages GMOs could cause. Pro-GMO supporters believe that promotion of research and development will ensure sustainable agriculture and feed starving peoples. What side do you choose?

It is important to begin by dissecting the issue scientifically. Therefore, let's begin with a series of definitions.

TERM
DEFINITION
Genetically
Of the genesis, or origin, of something; production or generation
Modified
To change or alter; esp., to change slightly or partially in character, form, etc.
Organism
Any individual animal, plant, bacterium, etc. having various parts or systems that function together as a whole to maintain life and its activities
Gene splicing
The technology most people think of when they think of a GMO is called gene splicing. The technology consists of adding a piece of DNA or new genes to an organism.
GMO
Is an organism--plant or animal--which has had a gene from an organism spliced into it through biotechnological means. Gene splicing is a new way of doing something mankind has done since Neolithic times--modifying plants and animals.
The EU-Commission Directive 90/220 definition of a GMO

Biological entities capable of replication or of transferring genetic material produced through genetic modification.

Products of GMOs, which are not capable of replication or transferring genetic material, such as tomato paste or soybean oil, are not included in this definition

Other terms used to refer to the process and products of modern biotechnology
Living Modified Organism (LMO)
Any living organism that possesses a novel combination of genetic material, obtained through the use of modern biotechnology
Transgenic Organism
Organism with a piece of DNA spliced into a chromosome in its cell. This "new piece" of DNA typically contains a gene
Genetically Engineered Organism (GEO)
An organism that has been modified by the application of recombinant DNA technology.
Recombinant DNA Technology
Isolating, manipulating, amplifying, cutting and splicing together identifiable sequences of DNA and then combining the sequence(s) into a cell

A Brief History of GMOs

The concept of altering an organism's genes for human benefit goes back over 20,000 years with selective breeding of deer, antelope and sheep. Ten thousand years ago societies were reportedly modifying strains of wheat for cultivation. Farmers have long crossed plants displaying favorable traits in order to produce an improved hybrid. Consequently, almost all of the food that is eaten today is no longer from genetically pure species. Dr. Harry Klee, a professor of horticultural sciences at the University of Florida who does research on genetic modification, says gene-splicing technology was developed in the United States of America around 1983.

Modern biotechnology is based on our understanding of biology at the level of genes, which determine the code that tells living things how to grow and develop. It includes genetic engineering, cloning, and other advanced technologies.

Medical uses

Biotechnology is best known within the area of pharmaceuticals, where it has a proven record of providing advance medicines to improve human health. One renowned example, aiding diabetics around the world, is insulin. Other medical uses include prosepteran for breast cancer, not infallible, but nevertheless, about the best prescription on the market at the moment. Biotechnology is used to manufacture human growth hormones to cure individuals with serious growth problems, such as midgets.

Agricultural uses

In 1996, economically significant amounts of GE food crops were first grown in the world. Most of them were planted in the USA. By 1999 33% of US corn (maize) acres, 44% of soybean acres and 55% of cotton acres were planted with GE seed.

In the area of agriculture, the growth of GMO plants and seeds has been remarkable. Sales grew from 20 million dollars in 1994 to 405 million dollars in 1997. That is annual growth rate between 1994 and 1997 of 173 percent. With the change in receptiveness that has taken place, forecasted growth for 1997 to 2002 is expected to only reach 38 percent, as the seeds of uncertainty rouse public inquiry about biotechnology.

YEAR
BIOTECHNOLOGY IN OUR HISTORY
BC
18,000
Middle Easterners domesticate and breed deer, antelope and sheep
5,000
Chinese domesticate and breed pigs
3,000
South American peoples select and breed potatoes and staple crops
2,000
Egyptians and Sumerians learn brewing and cheese making
300
Greeks developed grafting techniques for plant breeding
AD
1500
Fermenting come to the fore, leading to the development of sauerkraut and yogurt
1852
In Paris, an international "Corn Show" features varieties from Syria, Portugal, Hungary and Algeria
1700s
Naturalists identify hybrid plants, the offspring of breeding between two plant varieties
1859
Charles Darwin's book "origin of the Species" is published
1856
Gregor Mendel, the father of genetics, studied characteristics he could pass to future plant generations
1861
Louis Pasteur defines the role of micro-organisms and establishes the science of microbiology.
1900
European botanists use Mendel's Law to improve plant species. This is the beginning of 'selection'.
1901
Monsanto Chemical Works opens in St. Louis
1940
Oswald Avery isolates pure DNA
1941
Danish microbiologist A. Justin coins the term "genetic engineering"
1950
First regeneration of entire plants from an in vitro culture
1953
James Watson and Francis Crick describe double helix structure of DNA (receive Nobel Prices in 1962)
1970
Norman Borlaug, first plant breeder to win Nobel Prize for work on Green Revolution wheat varieties
1972
Hanley, president of Monsanto reveals the long-term strategy will emphasize research in biotechnology.
1973
Stanly Cohen & Hervert Boyer discover recombinant DNA technology, the birth of modern biotechnology
1980
Scientists transfer genetic information from 1organism to another, traits expressed in the recipient organism
1981
Chinese scientists become first to close a fish, a golden carp
1982
The first genetically engineered product, human insulin, is approved for sale in US
1987
Hepatitis B vaccine approved for use in Canada
1988
World's first field tests for genetically engineered canola take place in Canada
1990
The first food products modified by biotechnology, an enzyme for cheese production and yeast for baking
1993
Canadian Michael Smith wins the Nobel Prize in chemistry for work on reprogramming DNA segments
1996
Commercial production of biotechnology crops begin with corn, potato and canola
1997
Birth of Dolly the sheep announced as the first successful mammal cloned from an adult cell
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